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Epigenetic markers predict complications in patients with type 2 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 24 May 2022 Charlotte Ling and her research group have studied DNA methylations in the genome of different patient groups with type 2 diabetes. Photo: Kennet Ruona A new study by researchers at Lund University supports the notion that patients with type 2 diabetes should be divided into subgroups and given individualised t

https://www.ludc.lu.se/article/epigenetic-markers-predict-complications-patients-type-2-diabetes - 2025-02-23

Epigenetics can pave the way for individualised treatment of type 2 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 20 May 2022 Charlotte Ling, Tina Rönn and Karl Bacos carry out research at Lund University Diabetes Centre. They summarise some of the most important advancements within the field of epigenetics and diabetes in a review article. Photo: Petra Olsson Epigenetics has become an important tool for researchers endeavoring to und

https://www.ludc.lu.se/article/epigenetics-can-pave-way-individualised-treatment-type-2-diabetes - 2025-02-23

Newly discovered protein variants are key to insulin secretion

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 15 June 2022 From left: Ewelina Golec, Ben King and Anna Blom, three of the researchers behind new findings on insulin secretion. Photo: Tove Smeds. Insulin secretion into the bloodstream requires a protein called CD59. New research led by Lund University shows that the two protein variants that are responsible for this functi

https://www.ludc.lu.se/article/newly-discovered-protein-variants-are-key-insulin-secretion - 2025-02-23

Blood testing in children leads to better understanding of type 1 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 23 August 2022 Children taking part in the TEDDY study in Sweden have an increased risk of developing type 1 diabetes and are screened for the disease. Research nurse Jessica Melin takes a blood sample from one of the participants. Photograph: Kennet Ruona Why do some people develop type 1 diabetes and others do not? World

https://www.ludc.lu.se/article/blood-testing-children-leads-better-understanding-type-1-diabetes - 2025-02-23

New funding from Hjelt Diabetes Foundation to improve the understanding of diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 8 September 2022 Anja Schmidt-Christensen is studying microstructural changes in humans with diabetic kidney disease. She was recently awarded a grant from the Hjelt Diabetes Foundation for her research project. Photo: Petra Olsson Three researchers at Lund University Diabetes Centre (LUDC) have each been awarded a project

https://www.ludc.lu.se/article/new-funding-hjelt-diabetes-foundation-improve-understanding-diabetes - 2025-02-23

Study shows that the Piezo1 ion channel plays an important role in insulin secretion

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 11 October 2022 Enming Zhang is measuring insulin secretion in islets of Langerhans from healthy human donors where the expression of Piezo1 has been blocked. Photograph: Petra Olsson Impaired insulin secretion is closely associated with type 2 diabetes, but the process is not yet fully understood. A new study by researche

https://www.ludc.lu.se/article/study-shows-piezo1-ion-channel-plays-important-role-insulin-secretion - 2025-02-23

The Scientific Advisory Board: "We hope to see more data about the subgroups"

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 21 September 2022 Flemming Pociot and Søren Brunak from the Scientific Advisory Board were invited to the LUDC retreat recently. Photo: Petra Olsson We were interested to know what our Scientific Advisory Board think about the research currently underway at Lund University Diabetes Centre (LUDC), and invited Flemming Pocio

https://www.ludc.lu.se/article/scientific-advisory-board-we-hope-see-more-data-about-subgroups - 2025-02-23

Gut microbiome research indicates new bacteria and metformin associations

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 28 September 2022 Marju Orho-Melander is one of the lead authors of the article in Nature Communications, which is based in large-scale analyses of faeces and blood samples. Photograph: Petra Olsson A large-scale faeces and blood sample study indicates strong associations between gut bacteria and metabolites in the blood.

https://www.ludc.lu.se/article/gut-microbiome-research-indicates-new-bacteria-and-metformin-associations - 2025-02-23

Diabetes researcher Helena Elding Larsson wants to prevent type 1 diabetes from developing

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 25 October 2022 Helena Elding Larsson is awarded the Medeon stipend 2022 for her contribution to research into type 1 diabetes. The stipend will be presented during World Diabetes Day Skåne. Photo: Johan Persson Since Helena Elding Larsson began her career as a diabetes researcher and paediatrician, she has seen many impro

https://www.ludc.lu.se/article/diabetes-researcher-helena-elding-larsson-wants-prevent-type-1-diabetes-developing - 2025-02-23

Several diabetes researchers at LUDC receive grants from the Swedish Research Council

Published 14 November 2022 Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council. Photograph: Kennet Ruona Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council (Vetenskapsrådet). The six researchers are members of t

https://www.ludc.lu.se/article/several-diabetes-researchers-ludc-receive-grants-swedish-research-council - 2025-02-23

Learning more about the endocrine system could lead to fewer cases of type 2 diabetes and obesity

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 25 January 2023 Nurse Anna Hellman measures the blood pressure of a participant in a treatment study where researchers are investigating how the hormone vasopressin is affected by how much water we drink. Photo: Kennet Ruona How much water do we need to drink to stay healthy? How do different diets affect our metabolism? S

https://www.ludc.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-02-23

World Diabetes Day in Malmö 2015

Published 20 November 2015 World Diabetes Day in Malmö was all about science. Researchers told the latest on diabetes research from stem cells to diet and the smallest hade the opportunity to becoming scientists - and learn what makes a strawberry a strawberry .  Organisers:Lund University Diabetes Centre, Scania Hospital, Diabetes Society in Malmö/Lund and TEDDY.

https://www.ludc.lu.se/article/world-diabetes-day-malmo-2015 - 2025-02-23

ERC grant for research on diabetes

Published 26 January 2023 Charlotte Ling has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of research into epigenetics and biomarkers. Photo: Kennet Ruona Professor Charlotte Ling at Lund University Diabetes Centre (LUDC) has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of her su

https://www.ludc.lu.se/article/erc-grant-research-diabetes - 2025-02-23

Diabetes researcher Tove Fall is the recipient of the Leif C. Groop award 2023

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 14 February 2023 Diabetes researcher Tove Fall is the recipient of the Leif C. Groop award 2023 for outstanding research in the field of molecular epidemiology. Photo: Mikael Wallerstedt Tove Fall became a familiar face during the Covid-19 pandemic when she was often seen in Swedish media talking about the spread and progr

https://www.ludc.lu.se/article/diabetes-researcher-tove-fall-recipient-leif-c-groop-award-2023 - 2025-02-23

PAX5 – a gene strongly associated with impaired insulin secretion in type 2 diabetes

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 16 February 2023 Charlotte Ling, Tina Rönn, and Karl Bacos are three of the authors of a new study that has identified an important gene that affects insulin secretion. Photo: Petra Olsson Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-02-23

A genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects

By camilla [dot] selberg [at] med [dot] lu [dot] se (Camilla Selberg) - published 22 February 2023 First author Daniel E. Coral, LUDC researcher A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford univ

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-02-23

Swedish research about different forms of type 2 diabetes is relevant for Indian people

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 2 May 2023 Diabetes researcher Rashmi Prasad has led the research project about subgroups of type 2 diabetes in India. Photograph: Petra Olsson Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-02-23

Epigenetics and genetics help illustrate how diabetes care can be individualised

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 20 April 2023 Charlotte Ling’s research group has discovered epigenetic biomarkers that help them understand who will benefit from a common diabetes drug. Photo: Kennet Ruona Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? So

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-02-23

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 7 June 2023 Isabel Goncalves, Jiangming Sun, and Andreas Edsfeldt studying two atherosclerotic plaques. The study in JACC is based on a close collaboration between clinically active researchers and experts in bioinformatics. Photo: Petra Olsson A common cause of myocardial infarction and stroke is the rupture of atheroscle

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-02-23

Type 2 diabetes researchers receive support from the Hjelt Diabetes Foundation

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 5 September 2023 Jiangming Sun studies an atherosclerotic plaque. A goal with his research is to identify dangerous plaques at an early stage. The research project is now awarded a grant by the Hjelt Diabetes Foundation. Photograph: Petra Olsson Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-02-23